WHO recommendation on calcium supplementation during pregnancy for prevention of pre-eclampsia and its complications

Published by World Health Organization on Apr 3, 2025

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Abstract

WHO recommendation: Calcium supplementation during pregnancy for the prevention of pre-eclampsia and its complications 

 

I SBN 978-92-4-155045-1     

 

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Suggested citation. WHO recommendation: Calcium supplementation during pregnancy for the prevention of pre-eclampsia and its complications. Geneva: World Health Organization; 2018. Licence: CC BY-NC-SA 3.0 IGO. 

 

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PICOS

PICO 60.1

Population
All pregnant women, particularly those at higher risk of gestational hypertensive disorders
Intervention
Calcium supplementation-High-dose calcium supplementation (>1 g/day) with or without co-supplements
Comparator
No calcium supplementation or placebo
Outcomes

PICO 60.2

Population
All pregnant women, particularly those at higher risk of gestational hypertensive disorders
Intervention
Calcium supplementation-High-dose calcium supplementation in pregnancy, and by baseline dietary calcium
Comparator
Placebo or not treatment
Outcomes

PICO 60.3

Population
All pregnant women, particularly those at higher risk of gestational hypertensive disorders
Intervention
Low-dose calcium supplementation (< 1 g/day) with or without co-supplements
Comparator
Placebo
Outcomes

PICO 60.4

Population
All pregnant women, particularly those at higher risk of gestational hypertensive disorders
Intervention
Calcium suplemmentation-High dose
Comparator
Low dose calcium supplements
Outcomes