Evidence-based clinical practice guideline for the pharmacologic management of acute dental pain in adolescents, adults, and older adults

Published by Olivia Urquhart on May 29, 2025

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Abstract

Language

en

PICOS

PICO 10.1

Population
Adolescents, adults, and older adults undergoing surgical or simple tooth extraction(s)
Intervention
Bupivacaine (Long-acting local anesthetic)
Comparator
Short-acting local anesthetic
Outcomes

PICO 10.2

Population
Adoelscents, adults, and older adults undergoing simple or surgical tooth extraction(s)
Intervention
Bupivacaine (Long-acting local anesthetic)
Comparator
Lidocaine (short-acting local anesthetic)
Outcomes

PICO 10.3

Population
Adolescents, adults, and older adults undergoing surgical or simple tooth extraction(s)
Intervention
Bupivacaine (long-acting local anesthetic)
Comparator
Articaine (short-acting local anesthetic)
Outcomes

PICO 10.4

Population
Adoelscents, adults, and older adults undergoing simple or surgical tooth extraction(s)
Intervention
Bupivacaine (long-acting local anesthetic)
Comparator
Mepivacaine (short-acting local anesthetic)
Outcomes

PICO 60.1

Population
Adolescents, adults, and older adult with acute dental pain related to a toothache
Intervention
10% benzocaine
Comparator
20% Benzocaine
Outcomes

PICO 60.2

Population
Adolescents, adults, and older adult with acute dental pain related to a toothache
Intervention
10% benzocaine
Comparator
Placebo
Outcomes

PICO 60.3

Population
Adolescents, adults, and older adult with acute dental pain related to a toothache
Intervention
20% benzocaine
Comparator
Placebo
Outcomes

PICO 70.1

Population
Adoelscents, adults, and older adults undergoing simple or surgical tooth extraction(s)
Intervention
Glucocorticosteroids
Comparator
Placebo
Outcomes