NFOG guideline: Progesterone for prevention of preterm birth
Published by Jeannet Lauenborg on Jul 2, 2019
Nordic Federation of Obstetrics and Gynecology
Dept. of Obstetrics & Gynaecology and Dept. of Pediatrics, Nykoebing Falster Hospital, Denmark Universtiy Hospital Herlev, Herlev Hovedgade 75, 2730 Herlev, Denmark | ☏ +4522252207
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PICOS
PICO 30.1
Population
Women with a singleton pregnancy and a history of spontaneous abortion/preterm birth between 16+0 and 37 weeks unless explained by twins, placental abruption, trauma, conization or similar.Intervention
Progesterone, vaginal (100, 200 and 400 mg), before week 24Comparator
Placebo/NTOutcomes
PICO 30.2
Population
Women with a singleton pregnancy and a history of spontaneous abortion/preterm birth between 16+0 and 37 weeks unless explained by twins, placental abruption, trauma, conization or similar.Intervention
Progesterone, intramuscular, before week 24Comparator
Placebo/NTOutcomes
PICO 40.1
Population
Pregnant women with a singleton pregnancy and a short cervix below 25 mm; no uterine malformation and no cerclage.Intervention
Vaginal progesterone (100, 200 and 400 mg) before week 24Comparator
Placebo/NTOutcomes
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