NFOG guideline: Progesterone for prevention of preterm birth

Main Editor Jeannet Lauenborg
Language en
Last Update Jul 5, 2019
Published Date Jul 2, 2019
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Sponsors Nordic Federation of Obstetrics and Gynecology (NFOG)
Abstract

PICOS
PICO 3.1
P: Women with a singleton pregnancy and a history of spontaneous abortion/preterm birth between 16+0 and 37 weeks unless explained by twins, placental abruption, trauma, conization or similar.
I: Progesterone, vaginal (100, 200 and 400 mg), before week 24
C: Placebo/NT
O:

PICO 4.1
P: Pregnant women with a singleton pregnancy and a short cervix below 25 mm; no uterine malformation and no cerclage.
I: Vaginal progesterone (100, 200 and 400 mg) before week 24
C: Placebo/NT
O:

PICO 3.2
P: Women with a singleton pregnancy and a history of spontaneous abortion/preterm birth between 16+0 and 37 weeks unless explained by twins, placental abruption, trauma, conization or similar.
I: Progesterone, intramuscular, before week 24
C: Placebo/NT
O: