VTE, Thrombophilia, Antithrombotic Therapy and Pregnancy: A Norwegian adaptation of the 9th ed. of the ACCP Antithrombotic Therapy and Prevention of Thrombosis Evidence-based Clinical Practice Guidelines

Main Editor Anne Flem Jacobsen
Language en
Last Update Apr 17, 2015
Published Date Aug 4, 2015
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This chapter is translated from the Norwegian guideline chapter on thrombosis in pregnancy

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Abstract

PICOS
PICO 10.1
P: Prophylaxis of habitual abortion without known thrombophilia
I: LMWH + ASA
C: No treatment
O:

PICO 4.1
P: Pregnant women on long-term treatment for DVT and pulmonary embolism Acute embolism and thrombosis of unspecified deep veins of lower extremity I82.40, Pulmonary embolism I26, Pregnant woman 255409004, Pulmonary embolism without acute cor pulmonale I26.9, Pulmonary Embolism D011655, Pregnant Women D037841, Pulmonary embolism 59282003, Heparin 5224, Warfarin 11289, Heparin, Low-Molecular-Weight D006495, Warfarin D014859,
I: LMWH Acute embolism and thrombosis of unspecified deep veins of lower extremity I82.40, Pulmonary embolism I26, Pregnant woman 255409004, Pulmonary embolism without acute cor pulmonale I26.9, Pulmonary Embolism D011655, Pregnant Women D037841, Pulmonary embolism 59282003, Heparin 5224, Warfarin 11289, Heparin, Low-Molecular-Weight D006495, Warfarin D014859,
C: Warfarin Acute embolism and thrombosis of unspecified deep veins of lower extremity I82.40, Pulmonary embolism I26, Pregnant woman 255409004, Pulmonary embolism without acute cor pulmonale I26.9, Pulmonary Embolism D011655, Pregnant Women D037841, Pulmonary embolism 59282003, Heparin 5224, Warfarin 11289, Heparin, Low-Molecular-Weight D006495, Warfarin D014859,
O: Acute embolism and thrombosis of unspecified deep veins of lower extremity I82.40, Pulmonary embolism I26, Pregnant woman 255409004, Pulmonary embolism without acute cor pulmonale I26.9, Pulmonary Embolism D011655, Pregnant Women D037841, Pulmonary embolism 59282003, Heparin 5224, Warfarin 11289, Heparin, Low-Molecular-Weight D006495, Warfarin D014859,

PICO 6.1
P: Thrombosis with previous thromboembolism: Low risk
I: LMWH
C: No treatment
O:

PICO 5.1
P: Women undergoing assisted reproduction, without OHSS
I: LMWH
C: No treatment
O:

PICO 7.1
P: Thromboprophylaxis in homozygous Factor V Leiden and prothrombin 20210A mutation
I: LMWH
C: No treatment
O:

PICO 8.1
P: Cesarean section in pregnant women at low risk of VTE
I: LMWH
C: No treatment
O:

PICO 10.2
P: Prophylaxis of habitual abortion without known thrombophilia
I: ASA
C: No treatment
O:

PICO 5.2
P: Women undergoing assisted reproduction, with OHSS
I: LMWH
C: No treatment
O:

PICO 7.2
P: Thromboprophylaxis in heterozygous factor V Leiden and prothrombin 20210A mutation and family history, Leiden and prothrombin combination
I: LMWH
C: No treatment
O:

PICO 8.2
P: Cesarean section in pregnant women at moderate risk of VTE
I: LMWH
C: No treatment
O:

PICO 10.3
P: Prophylaxis of antiphospholipid syndrome and habitual abortions Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Acetylsalisylate B01A C06, Heparin B01A B01, Aspirin 1191, Heparin 5224, Heparin D006493, Aspirin D001241, Antiphospholipid Syndrome D016736, Abortion, Habitual D000026,
I: UFH plus ASA Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Acetylsalisylate B01A C06, Heparin B01A B01, Aspirin 1191, Heparin 5224, Heparin D006493, Aspirin D001241, Antiphospholipid Syndrome D016736, Abortion, Habitual D000026,
C: ASA Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Acetylsalisylate B01A C06, Heparin B01A B01, Aspirin 1191, Heparin 5224, Heparin D006493, Aspirin D001241, Antiphospholipid Syndrome D016736, Abortion, Habitual D000026,
O: Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Acetylsalisylate B01A C06, Heparin B01A B01, Aspirin 1191, Heparin 5224, Heparin D006493, Aspirin D001241, Antiphospholipid Syndrome D016736, Abortion, Habitual D000026,

PICO 6.3
P: Thrombosis with previous thromboembolism: Moderate-high risk
I: LMWH
C: No treatment
O:

PICO 7.3
P: Thromboprophylaxis in protein C and protein S deficiency with a family history
I: LMWH
C: No treatment
O:

PICO 8.3
P: Cesarean section in pregnant women at high risk of VTE
I: LMWH
C: No treatment
O:

PICO 10.4
P: Prevention of preeclampsia in pregnant women without known thrombophilia
I: ASA
C: No treatment
O:

PICO 7.4
P: Thromboprophylaxis in antithrombin deficiency with or without a family history
I: LMWH
C: No treatment
O:

PICO 7.5
P: Thromboprophylaxis in Antiphospholipid Syndrome and habitual abortions Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Heparin B01A B01, ASA B01A C06, Acetyl salicylate 91101, Heparin 5224, Antibodies, Antiphospholipid D017152, Antibodies, Anticardiolipin D017153, Abortion, Habitual D000026, Heparin D006493, Aspirin D001241,
I: UFH plus ASA Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Heparin B01A B01, ASA B01A C06, Acetyl salicylate 91101, Heparin 5224, Antibodies, Antiphospholipid D017152, Antibodies, Anticardiolipin D017153, Abortion, Habitual D000026, Heparin D006493, Aspirin D001241,
C: ASA Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Heparin B01A B01, ASA B01A C06, Acetyl salicylate 91101, Heparin 5224, Antibodies, Antiphospholipid D017152, Antibodies, Anticardiolipin D017153, Abortion, Habitual D000026, Heparin D006493, Aspirin D001241,
O: Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Heparin B01A B01, ASA B01A C06, Acetyl salicylate 91101, Heparin 5224, Antibodies, Antiphospholipid D017152, Antibodies, Anticardiolipin D017153, Abortion, Habitual D000026, Heparin D006493, Aspirin D001241,