Australian Guidelines for the treatment of Acute Stress Disorder, Posttraumatic Stress Disorder, and Complex PTSD
Main Editor
Dr Ros Lethbridge
Language
en
Last Update
Feb 20, 2020
Published Date
Feb 20, 2020
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Abstract
PICOS
PICO 1.1
P: Children and adolescents within the first three months post traumatic event
I: Psychoeducation
C: Waitlist/ treatment as usual
O:
P: Children and adolescents within the first three months post traumatic event
I: Psychoeducation
C: Waitlist/ treatment as usual
O:
PICO 2.1
P: Children and adolescents within the first three months post traumatic event
I: Stepped preventative care intervention
C: Waitlist/ treatment as usual
O:
P: Children and adolescents within the first three months post traumatic event
I: Stepped preventative care intervention
C: Waitlist/ treatment as usual
O:
PICO 3.1
P: Children and adolescents within the first three months post traumatic event
I: Propranolol
C: Placebo
O:
P: Children and adolescents within the first three months post traumatic event
I: Propranolol
C: Placebo
O:
PICO 1.1
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for child
C: Waitlist/ treatment as usual
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for child
C: Waitlist/ treatment as usual
O:
PICO 2.1
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Sertraline
C: Placebo
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Sertraline
C: Placebo
O:
PICO 3.1
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Mind-body skills group
C: Waitlist/ treatment as usual
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Mind-body skills group
C: Waitlist/ treatment as usual
O:
PICO 5.1
P: Adults
I: Attention bias modification training (ABMT)
C: No training control
O:
P: Adults
I: Attention bias modification training (ABMT)
C: No training control
O:
PICO 1.1
P: Adults within the first three months post-traumatic event
I: Group debriefing
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post-traumatic event
I: Group debriefing
C: Waitlist/ treatment as usual
O:
PICO 2.1
P: Adults in the first three months post traumatic event
I: Brief individual trauma processing therapy
C: Waitlist/ treatment as usual
O:
P: Adults in the first three months post traumatic event
I: Brief individual trauma processing therapy
C: Waitlist/ treatment as usual
O:
PICO 3.1
P: Adults within the first three months post traumatic event
I: Trauma-focused CBT
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post traumatic event
I: Trauma-focused CBT
C: Waitlist/ treatment as usual
O:
PICO 4.1
P: Adults within the first three months of a traumatic event
I: Docosahexaenoic Acid
C: Placebo
O:
P: Adults within the first three months of a traumatic event
I: Docosahexaenoic Acid
C: Placebo
O:
PICO 1.1
P: Adults with PTSD
I: Trauma focused-CBT
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Trauma focused-CBT
C: Waitlist/ treatment as usual
O:
PICO 2.1
P: Adults with PTSD
I: Selective serotonin re-uptake inhibitors (SSRIs)
C: Placebo
O:
P: Adults with PTSD
I: Selective serotonin re-uptake inhibitors (SSRIs)
C: Placebo
O:
PICO 3.1
P: Adults with PTSD
I: Yoga
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Yoga
C: Waitlist/ treatment as usual
O:
PICO 1.2
P: Children and adolescents within the first three months post traumatic event
I: Self-directed online psychoeducation for caregivers and children
C: Waitlist/ usual care
O:
P: Children and adolescents within the first three months post traumatic event
I: Self-directed online psychoeducation for caregivers and children
C: Waitlist/ usual care
O:
PICO 2.2
P: Children and adolescents within the first three months post traumatic event
I: Child and Family Traumatic Stress Intervention (CFTSI)
C: Supportive care
O:
P: Children and adolescents within the first three months post traumatic event
I: Child and Family Traumatic Stress Intervention (CFTSI)
C: Supportive care
O:
PICO 1.2
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for child
C: Non-directive counselling
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for child
C: Non-directive counselling
O:
PICO 3.2
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused expressive art therapy
C: Waitlist/ treatment as usual
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused expressive art therapy
C: Waitlist/ treatment as usual
O:
PICO 5.2
P: Adults
I: Attention bias modification training (ABMT)
C: Attention Control Training (ACT)
O:
P: Adults
I: Attention bias modification training (ABMT)
C: Attention Control Training (ACT)
O:
PICO 1.2
P: Adults within the first three months post-traumatic event
I: Individual debriefing
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post-traumatic event
I: Individual debriefing
C: Waitlist/ treatment as usual
O:
PICO 2.2
P: Adults in the first three months post traumatic event
I: Brief individual trauma processing therapy
C: Supportive listening
O:
P: Adults in the first three months post traumatic event
I: Brief individual trauma processing therapy
C: Supportive listening
O:
PICO 3.2
P: Adults within the first three months post-traumatic event
I: Trauma-focused CBT
C: Supportive counselling
O:
P: Adults within the first three months post-traumatic event
I: Trauma-focused CBT
C: Supportive counselling
O:
PICO 4.2
P: Adults within the first three months of a traumatic event
I: Escitalopram
C: Placebo
O:
P: Adults within the first three months of a traumatic event
I: Escitalopram
C: Placebo
O:
PICO 1.2
P: Adults with PTSD
I: Trauma-focused CBT
C: Non-trauma focused CBT
O:
P: Adults with PTSD
I: Trauma-focused CBT
C: Non-trauma focused CBT
O:
PICO 2.2
P: Adults with PTSD
I: SSRIs- Fluoxetine
C: Placebo
O:
P: Adults with PTSD
I: SSRIs- Fluoxetine
C: Placebo
O:
PICO 3.2
P: Adults with PTSD
I: Acupuncture
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Acupuncture
C: Waitlist/ treatment as usual
O:
PICO 1.3
P: Children and adolescents within the first three months post traumatic event
I: Self-directed online psychoeducation intervention for children only
C: Waitlist/ treatment as usual
O:
P: Children and adolescents within the first three months post traumatic event
I: Self-directed online psychoeducation intervention for children only
C: Waitlist/ treatment as usual
O:
PICO 2.3
P: Children and adolescents within the first three months post traumatic event
I: Brief trauma-focused CBT
C: Waitlist/ treatment as usual
O:
P: Children and adolescents within the first three months post traumatic event
I: Brief trauma-focused CBT
C: Waitlist/ treatment as usual
O:
PICO 1.3
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for child
C: Psychoeducation
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for child
C: Psychoeducation
O:
PICO 5.3
P: Adults
I: Attention Control Training (ACT)
C: No training control
O:
P: Adults
I: Attention Control Training (ACT)
C: No training control
O:
PICO 1.3
P: Adults within the first three months post-traumatic event
I: EMDR
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post-traumatic event
I: EMDR
C: Waitlist/ treatment as usual
O:
PICO 2.3
P: Adults in the first three months post traumatic event
I: Three step early intervention for mothers of infants born prematurely
C: Waitlist/ treatment as usual
O:
P: Adults in the first three months post traumatic event
I: Three step early intervention for mothers of infants born prematurely
C: Waitlist/ treatment as usual
O:
PICO 3.3
P: Adults within the first three months post-traumatic event
I: Brief prolonged exposure-based interventions
C: Supportive counselling
O:
P: Adults within the first three months post-traumatic event
I: Brief prolonged exposure-based interventions
C: Supportive counselling
O:
PICO 4.3
P: Adults within the first three months post traumatic event
I: Hydrocortisone
C: Placebo
O:
P: Adults within the first three months post traumatic event
I: Hydrocortisone
C: Placebo
O:
PICO 1.3
P: Adults with PTSD
I: Trauma-focused CBT
C: Present Centred Therapy
O:
P: Adults with PTSD
I: Trauma-focused CBT
C: Present Centred Therapy
O:
PICO 2.3
P: Adults with PTSD
I: SSRIs- Paroxetine
C: Placebo
O:
P: Adults with PTSD
I: SSRIs- Paroxetine
C: Placebo
O:
PICO 3.3
P: Adults with PTSD
I: Acupuncture
C: Trauma-focused CBT
O:
P: Adults with PTSD
I: Acupuncture
C: Trauma-focused CBT
O:
PICO 1.4
P: Children and adolescents within the first three months post traumatic event
I: Self-directed online psychoeducation for caregivers only
C: Waitlist/ usual care
O:
P: Children and adolescents within the first three months post traumatic event
I: Self-directed online psychoeducation for caregivers only
C: Waitlist/ usual care
O:
PICO 2.4
P: Children and adolescents within the first three months post traumatic event
I: Trauma-focused CBT (NET)
C: Meditation
O:
P: Children and adolescents within the first three months post traumatic event
I: Trauma-focused CBT (NET)
C: Meditation
O:
PICO 1.4
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for child
C: EMDR
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for child
C: EMDR
O:
PICO 5.4
P: Adults
I: Single session Attention Bias Modification Training (ABMT)
C: Attention Control Training (ACT)
O:
P: Adults
I: Single session Attention Bias Modification Training (ABMT)
C: Attention Control Training (ACT)
O:
PICO 1.4
P: Adults within the first three months post traumatic event
I: EMDR
C: Reassurance
O:
P: Adults within the first three months post traumatic event
I: EMDR
C: Reassurance
O:
PICO 2.4
P: Adults in the first three months post traumatic event
I: Brief dyadic therapies
C: Waitlist/ treatment as usual
O:
P: Adults in the first three months post traumatic event
I: Brief dyadic therapies
C: Waitlist/ treatment as usual
O:
PICO 3.4
P: Adults within the first three months post-traumatic event
I: Brief CPT-based interventions
C: Supportive counselling
O:
P: Adults within the first three months post-traumatic event
I: Brief CPT-based interventions
C: Supportive counselling
O:
PICO 4.4
P: Adults within the first three months post traumatic event
I: Oxytocin
C: Placebo
O:
P: Adults within the first three months post traumatic event
I: Oxytocin
C: Placebo
O:
PICO 1.4
P: Adults with PTSD
I: Trauma-focused CBT
C: Supportive counselling
O:
P: Adults with PTSD
I: Trauma-focused CBT
C: Supportive counselling
O:
PICO 2.4
P: Adults with PTSD
I: SSRIs- Sertraline
C: Placebo
O:
P: Adults with PTSD
I: SSRIs- Sertraline
C: Placebo
O:
PICO 3.4
P: Adults with PTSD
I: Physical exercise
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Physical exercise
C: Waitlist/ treatment as usual
O:
PICO 1.5
P: Children and adolescents within the first three months post traumatic event
I: Individual psychological debriefing
C: Waitlist/ usual care
O:
P: Children and adolescents within the first three months post traumatic event
I: Individual psychological debriefing
C: Waitlist/ usual care
O:
PICO 1.5
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Group trauma-focused CBT for child
C: Waitlist/ treatment as usual
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Group trauma-focused CBT for child
C: Waitlist/ treatment as usual
O:
PICO 5.5
P: Adults
I: MAPS resilience training
C: Training as usual (TAU)
O:
P: Adults
I: MAPS resilience training
C: Training as usual (TAU)
O:
PICO 1.5
P: Adults within the first three months post-traumatic event
I: Individual psychoeducation/self-help
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post-traumatic event
I: Individual psychoeducation/self-help
C: Waitlist/ treatment as usual
O:
PICO 2.5
P: Adults in the first three months post traumatic event
I: Guided internet-based CBT
C: Waitlist/ treatment as usual
O:
P: Adults in the first three months post traumatic event
I: Guided internet-based CBT
C: Waitlist/ treatment as usual
O:
PICO 3.5
P: Adults within the first three months post-traumatic event
I: Trauma-focused CBT
C: Relaxation
O:
P: Adults within the first three months post-traumatic event
I: Trauma-focused CBT
C: Relaxation
O:
PICO 4.5
P: Adults within the first three months post traumatic event
I: Propranolol
C: Placebo
O:
P: Adults within the first three months post traumatic event
I: Propranolol
C: Placebo
O:
PICO 1.5
P: Adults with PTSD
I: Trauma-focused CBT
C: Psychodynamic therapy
O:
P: Adults with PTSD
I: Trauma-focused CBT
C: Psychodynamic therapy
O:
PICO 2.5
P: Adults with PTSD
I: Citalopram
C: Sertraline
O:
P: Adults with PTSD
I: Citalopram
C: Sertraline
O:
PICO 3.5
P: Adults with PTSD
I: Mantram repetition
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Mantram repetition
C: Waitlist/ treatment as usual
O:
PICO 1.6
P: Children and adolescents within the first three months post traumatic event
I: Brief CBT
C: Waitlist/usual care
O:
P: Children and adolescents within the first three months post traumatic event
I: Brief CBT
C: Waitlist/usual care
O:
PICO 1.6
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Group trauma-focused CBT for child
C: Group resilience building intervention
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Group trauma-focused CBT for child
C: Group resilience building intervention
O:
PICO 5.6
P: Adults
I: Heart rate variability biofeedback (HRVB)
C: Control
O:
P: Adults
I: Heart rate variability biofeedback (HRVB)
C: Control
O:
PICO 1.6
P: Adults within the first three months post traumatic event
I: Group stress management
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post traumatic event
I: Group stress management
C: Waitlist/ treatment as usual
O:
PICO 2.6
P: Adults in the first three months post traumatic event
I: Intensive care diaries
C: Waitlist/ treatment as usual
O:
P: Adults in the first three months post traumatic event
I: Intensive care diaries
C: Waitlist/ treatment as usual
O:
PICO 3.6
P: Adults within the first three months post-traumatic event
I: Trauma-focused CBT
C: Structured writing therapy
O:
P: Adults within the first three months post-traumatic event
I: Trauma-focused CBT
C: Structured writing therapy
O:
PICO 4.6
P: Adults within the first three months post traumatic event
I: Gabapentin
C: Placebo
O:
P: Adults within the first three months post traumatic event
I: Gabapentin
C: Placebo
O:
PICO 1.6
P: Adults with PTSD
I: Trauma-focused CBT
C: Interpersonal Therapy (IPT)
O:
P: Adults with PTSD
I: Trauma-focused CBT
C: Interpersonal Therapy (IPT)
O:
PICO 2.6
P: Adults with PTSD
I: Sertraline
C: Nefazadone
O:
P: Adults with PTSD
I: Sertraline
C: Nefazadone
O:
PICO 3.6
P: Adults with PTSD
I: Mantram repetition
C: Present centred therapy
O:
P: Adults with PTSD
I: Mantram repetition
C: Present centred therapy
O:
PICO 1.7
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver
C: Waitlist/ treatment as usual
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver
C: Waitlist/ treatment as usual
O:
PICO 5.7
P: Adults
I: Heart rate variability biofeedback (HRVB)
C: Cognitive bias modification for interpretation (CBM-I)
O:
P: Adults
I: Heart rate variability biofeedback (HRVB)
C: Cognitive bias modification for interpretation (CBM-I)
O:
PICO 1.7
P: Adults within the first three months post traumatic event
I: Computerised visuospatial task
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post traumatic event
I: Computerised visuospatial task
C: Waitlist/ treatment as usual
O:
PICO 2.7
P: Adults in the first three months post traumatic event
I: Brief Interpersonal Counselling
C: Waitlist/ treatment as usual
O:
P: Adults in the first three months post traumatic event
I: Brief Interpersonal Counselling
C: Waitlist/ treatment as usual
O:
PICO 3.7
P: Adults within the first three months post-traumatic event
I: Trauma-focused CBT
C: Self-help program
O:
P: Adults within the first three months post-traumatic event
I: Trauma-focused CBT
C: Self-help program
O:
PICO 1.7
P: Adults with PTSD
I: Trauma-focused CBT (CPT)
C: Dialogical exposure therapy (DET)
O:
P: Adults with PTSD
I: Trauma-focused CBT (CPT)
C: Dialogical exposure therapy (DET)
O:
PICO 2.7
P: Adults with PTSD
I: Serotonin and nor-adrenaline re-uptake inhibitors- Venlafaxine
C: Placebo
O:
P: Adults with PTSD
I: Serotonin and nor-adrenaline re-uptake inhibitors- Venlafaxine
C: Placebo
O:
PICO 3.7
P: Adults with PTSD
I: Group music therapy
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Group music therapy
C: Waitlist/ treatment as usual
O:
PICO 1.8
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver
C: Trauma-focused CBT for caregiver and child
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver
C: Trauma-focused CBT for caregiver and child
O:
PICO 5.8
P: Adults
I: Cognitive bias modification for interpretation (CBM-I)
C: Control
O:
P: Adults
I: Cognitive bias modification for interpretation (CBM-I)
C: Control
O:
PICO 1.8
P: Adults within the first three months post traumatic event
I: Group 512 PIM
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post traumatic event
I: Group 512 PIM
C: Waitlist/ treatment as usual
O:
PICO 2.8
P: Adults in the first three months post traumatic event
I: Collaborative care
C: Waitlist/ treatment as usual
O:
P: Adults in the first three months post traumatic event
I: Collaborative care
C: Waitlist/ treatment as usual
O:
PICO 3.8
P: Adults within the first three months post-traumatic event
I: Prolonged exposure
C: Cognitive therapy
O:
P: Adults within the first three months post-traumatic event
I: Prolonged exposure
C: Cognitive therapy
O:
PICO 1.8
P: Adults with PTSD
I: Trauma-focused CBT
C: Psychoeducation
O:
P: Adults with PTSD
I: Trauma-focused CBT
C: Psychoeducation
O:
PICO 2.8
P: Adults with PTSD
I: Venlafaxine
C: Sertraline
O:
P: Adults with PTSD
I: Venlafaxine
C: Sertraline
O:
PICO 3.8
P: Adults with PTSD
I: Nature adventure therapy
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Nature adventure therapy
C: Waitlist/ treatment as usual
O:
PICO 1.9
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver
C: Trauma-focused CBT for child
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver
C: Trauma-focused CBT for child
O:
PICO 5.9
P: Adults
I: Stress inoculation training (SIT)
C: Control
O:
P: Adults
I: Stress inoculation training (SIT)
C: Control
O:
PICO 1.9
P: Adults within the first three months post traumatic event
I: Group 512 PIM
C: Group debriefing
O:
P: Adults within the first three months post traumatic event
I: Group 512 PIM
C: Group debriefing
O:
PICO 2.9
P: Adults in the first three months post traumatic event
I: Supported psychoeducational intervention
C: Waitlist/ treatment as usual
O:
P: Adults in the first three months post traumatic event
I: Supported psychoeducational intervention
C: Waitlist/ treatment as usual
O:
PICO 3.9
P: Adults within the first three months post-traumatic event
I: Prolonged exposure
C: Wait list
O:
P: Adults within the first three months post-traumatic event
I: Prolonged exposure
C: Wait list
O:
PICO 1.9
P: Adults with PTSD
I: Trauma-focused CBT
C: Relaxation training
O:
P: Adults with PTSD
I: Trauma-focused CBT
C: Relaxation training
O:
PICO 2.9
P: Adults with PTSD
I: Nor-adrenergic and specific serotonin antidepressant- Mirtazapine
C: Placebo
O:
P: Adults with PTSD
I: Nor-adrenergic and specific serotonin antidepressant- Mirtazapine
C: Placebo
O:
PICO 3.9
P: Adults with PTSD
I: Repetitive transcranial magnetic stimulation (rTMS)
C: Sham TMS
O:
P: Adults with PTSD
I: Repetitive transcranial magnetic stimulation (rTMS)
C: Sham TMS
O:
PICO 1.10
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver and child
C: Waitlist/ treatment as usual
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver and child
C: Waitlist/ treatment as usual
O:
PICO 1.10
P: Adults within the first three months post traumatic event
I: Group education
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post traumatic event
I: Group education
C: Waitlist/ treatment as usual
O:
PICO 2.10
P: Adults in the first three months post traumatic event
I: Telephone-based CBT
C: Waitlist/ treatment as usual
O:
P: Adults in the first three months post traumatic event
I: Telephone-based CBT
C: Waitlist/ treatment as usual
O:
PICO 3.10
P: Adults within the first three months post traumatic event
I: Cognitive therapy
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post traumatic event
I: Cognitive therapy
C: Waitlist/ treatment as usual
O:
PICO 1.10
P: Adults with PTSD
I: Brief Eclectic Psychotherapy
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Brief Eclectic Psychotherapy
C: Waitlist/ treatment as usual
O:
PICO 2.10
P: Adults with PTSD
I: Tricyclic antidepressant- Amitriptyline
C: Placebo
O:
P: Adults with PTSD
I: Tricyclic antidepressant- Amitriptyline
C: Placebo
O:
PICO 3.10
P: Adults with PTSD
I: Neurofeedback
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Neurofeedback
C: Waitlist/ treatment as usual
O:
PICO 1.11
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver and child
C: Non-directive counselling
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver and child
C: Non-directive counselling
O:
PICO 1.11
P: Adults within the first three months post-traumatic event
I: Reassurance
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post-traumatic event
I: Reassurance
C: Waitlist/ treatment as usual
O:
PICO 2.11
P: Adults in the first three months post traumatic event
I: Telephone + Internet-based CBT
C: Critical illness educational intervention
O:
P: Adults in the first three months post traumatic event
I: Telephone + Internet-based CBT
C: Critical illness educational intervention
O:
PICO 3.11
P: Adults within the first three months post traumatic event
I: Brief EMDR
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post traumatic event
I: Brief EMDR
C: Waitlist/ treatment as usual
O:
PICO 1.11
P: Adults with PTSD
I: Cognitive Processing Therapy
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Cognitive Processing Therapy
C: Waitlist/ treatment as usual
O:
PICO 2.11
P: Adults with PTSD
I: Tricyclic antidepressant- Imipramine
C: Placebo
O:
P: Adults with PTSD
I: Tricyclic antidepressant- Imipramine
C: Placebo
O:
PICO 3.11
P: Adults with PTSD
I: Somatic experiencing
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Somatic experiencing
C: Waitlist/ treatment as usual
O:
PICO 1.12
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver and child
C: EMDR
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver and child
C: EMDR
O:
PICO 1.12
P: Adults within the first three months post traumatic event
I: Brief EMDR
C: Critical Incident Stress Debriefing (CSID)
O:
P: Adults within the first three months post traumatic event
I: Brief EMDR
C: Critical Incident Stress Debriefing (CSID)
O:
PICO 1.12
P: Adults within the first three months post traumatic event
I: Trauma-focused counselling
C: Heart stress counselling
O:
P: Adults within the first three months post traumatic event
I: Trauma-focused counselling
C: Heart stress counselling
O:
PICO 2.12
P: Adults in the first three months post traumatic event
I: Communication facilitator in an intensive care setting
C: Waitlist/ treatment as usual
O:
P: Adults in the first three months post traumatic event
I: Communication facilitator in an intensive care setting
C: Waitlist/ treatment as usual
O:
PICO 1.12
P: Adults with PTSD
I: Cognitive processing therapy (CPT)
C: Prolonged exposure (PE)
O:
P: Adults with PTSD
I: Cognitive processing therapy (CPT)
C: Prolonged exposure (PE)
O:
PICO 2.12
P: Adults with PTSD
I: Monoamine oxidase inhibitors- Brofaromine
C: Placebo
O:
P: Adults with PTSD
I: Monoamine oxidase inhibitors- Brofaromine
C: Placebo
O:
PICO 3.12
P: Adults with PTSD
I: Saikokaishikankyoto
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Saikokaishikankyoto
C: Waitlist/ treatment as usual
O:
PICO 1.13
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver and child
C: Trauma-focused CBT for child
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver and child
C: Trauma-focused CBT for child
O:
PICO 2.13
P: Adults within the first three months post traumatic event
I: Nurse-led intensive care recovery program
C: WL/TAU
O:
P: Adults within the first three months post traumatic event
I: Nurse-led intensive care recovery program
C: WL/TAU
O:
PICO 3.13
P: Adults within the first three months post-traumatic event
I: Present centered therapy (HOPE)
C: Waitlist/TAU
O:
P: Adults within the first three months post-traumatic event
I: Present centered therapy (HOPE)
C: Waitlist/TAU
O:
PICO 1.13
P: Adults with PTSD
I: Cognitive Therapy
C: Waitlist
O:
P: Adults with PTSD
I: Cognitive Therapy
C: Waitlist
O:
PICO 2.13
P: Adults with PTSD
I: Monoamine oxidase inhibitors- Phenelzine
C: Placebo
O:
P: Adults with PTSD
I: Monoamine oxidase inhibitors- Phenelzine
C: Placebo
O:
PICO 3.13
P: Adults with PTSD
I: Mindfulness-based stress reduction
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Mindfulness-based stress reduction
C: Waitlist/ treatment as usual
O:
PICO 1.14
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver and child
C: Stepped care trauma-focused CBT for caregiver and child
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Trauma-focused CBT for caregiver and child
C: Stepped care trauma-focused CBT for caregiver and child
O:
PICO 3.14
P: Adults within the first three months post traumatic event
I: Structured writing therapy
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post traumatic event
I: Structured writing therapy
C: Waitlist/ treatment as usual
O:
PICO 1.14
P: Adults with PTSD
I: Narrative Exposure Therapy (NET)
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Narrative Exposure Therapy (NET)
C: Waitlist/ treatment as usual
O:
PICO 2.14
P: Adults with PTSD
I: Phenelzine
C: Imipramine
O:
P: Adults with PTSD
I: Phenelzine
C: Imipramine
O:
PICO 3.14
P: Adults with PTSD
I: Mindfulness-based stress reduction
C: Present centred therapy
O:
P: Adults with PTSD
I: Mindfulness-based stress reduction
C: Present centred therapy
O:
PICO 1.15
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Group trauma-focused CBT for caregiver and child
C: Supportive group therapy
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Group trauma-focused CBT for caregiver and child
C: Supportive group therapy
O:
PICO 3.15
P: Adults within the first three months post-traumatic event
I: Structured writing therapy
C: Psychoeducation
O:
P: Adults within the first three months post-traumatic event
I: Structured writing therapy
C: Psychoeducation
O:
PICO 1.15
P: Adults with PTSD
I: Prolonged Exposure
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Prolonged Exposure
C: Waitlist/ treatment as usual
O:
PICO 2.15
P: Adults with PTSD
I: Antipsychotics- Olanzapine
C: Placebo
O:
P: Adults with PTSD
I: Antipsychotics- Olanzapine
C: Placebo
O:
PICO 3.15
P: Adults with PTSD
I: Mindfulness-based stress reduction
C: Psychoeducation
O:
P: Adults with PTSD
I: Mindfulness-based stress reduction
C: Psychoeducation
O:
PICO 1.16
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Individual and group trauma-focused CBT for caregiver and child
C: Waitlist/ treatment as usual
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Individual and group trauma-focused CBT for caregiver and child
C: Waitlist/ treatment as usual
O:
PICO 3.16
P: Adults within the first three months post traumatic event
I: Internet-based guided self-help
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post traumatic event
I: Internet-based guided self-help
C: Waitlist/ treatment as usual
O:
PICO 1.16
P: Adults with PTSD
I: Prolonged exposure
C: Health Education
O:
P: Adults with PTSD
I: Prolonged exposure
C: Health Education
O:
PICO 2.16
P: Adults with PTSD
I: Antipsychotics- Quetiapine
C: Placebo
O:
P: Adults with PTSD
I: Antipsychotics- Quetiapine
C: Placebo
O:
PICO 3.16
P: Adults with PTSD
I: Attentional bias modification
C: Attention control placebo
O:
P: Adults with PTSD
I: Attentional bias modification
C: Attention control placebo
O:
PICO 1.17
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Eye Movement Desensitization and Reprocessing (EMDR)
C: Waitlist/ treatment as usual
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Eye Movement Desensitization and Reprocessing (EMDR)
C: Waitlist/ treatment as usual
O:
PICO 3.17
P: Adults within the first three months post traumatic event
I: Behavioural activation
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post traumatic event
I: Behavioural activation
C: Waitlist/ treatment as usual
O:
PICO 1.17
P: Adults with PTSD
I: Single Session CBT-T
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Single Session CBT-T
C: Waitlist/ treatment as usual
O:
PICO 2.17
P: Adults with PTSD
I: Antiepileptics- Divalproex
C: Placebo
O:
P: Adults with PTSD
I: Antiepileptics- Divalproex
C: Placebo
O:
PICO 3.17
P: Adults with PTSD
I: Hypnotherapy
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Hypnotherapy
C: Waitlist/ treatment as usual
O:
PICO 1.18
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Non-directive counselling
C: Waitlist/ treatment as usual
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Non-directive counselling
C: Waitlist/ treatment as usual
O:
PICO 3.18
P: Adults within the first three months post traumatic event
I: Supportive counselling
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post traumatic event
I: Supportive counselling
C: Waitlist/ treatment as usual
O:
PICO 1.18
P: Adults with PTSD
I: Reconsolidation of traumatic memories (RTM)
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Reconsolidation of traumatic memories (RTM)
C: Waitlist/ treatment as usual
O:
PICO 2.18
P: Adults with PTSD
I: Antiepileptics- Lamotrigine
C: Placebo
O:
P: Adults with PTSD
I: Antiepileptics- Lamotrigine
C: Placebo
O:
PICO 3.18
P: Adults with PTSD
I: Hypnotherapy
C: Trauma-focused CBT
O:
P: Adults with PTSD
I: Hypnotherapy
C: Trauma-focused CBT
O:
PICO 1.19
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Group psychoeducation
C: Waitlist/ treatment as usual
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Group psychoeducation
C: Waitlist/ treatment as usual
O:
PICO 3.19
P: Adults within the first three months post-traumatic event
I: Stepped/collaborative care
C: Waitlist/ treatment as usual
O:
P: Adults within the first three months post-traumatic event
I: Stepped/collaborative care
C: Waitlist/ treatment as usual
O:
PICO 1.19
P: Adults with PTSD
I: EMDR
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: EMDR
C: Waitlist/ treatment as usual
O:
PICO 2.19
P: Adults with PTSD
I: Antiepileptics- Tiagabine
C: Placebo
O:
P: Adults with PTSD
I: Antiepileptics- Tiagabine
C: Placebo
O:
PICO 3.19
P: Adults with PTSD
I: Electroacupuncture
C: Paroxetine
O:
P: Adults with PTSD
I: Electroacupuncture
C: Paroxetine
O:
PICO 1.20
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Family therapy
C: Waitlist/ treatment as usual
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Family therapy
C: Waitlist/ treatment as usual
O:
PICO 3.20
P: Adults within the first three months post-traumatic event
I: Computerised neurobehavioural training
C: Computerised games control condition
O:
P: Adults within the first three months post-traumatic event
I: Computerised neurobehavioural training
C: Computerised games control condition
O:
PICO 1.20
P: Adults with PTSD
I: EMDR
C: Trauma-focused CBT
O:
P: Adults with PTSD
I: EMDR
C: Trauma-focused CBT
O:
PICO 2.20
P: Adults with PTSD
I: Antiepileptics- Topiramate
C: Placebo
O:
P: Adults with PTSD
I: Antiepileptics- Topiramate
C: Placebo
O:
PICO 3.20
P: Adults with PTSD
I: Transcendental meditation
C: Prolonged exposure
O:
P: Adults with PTSD
I: Transcendental meditation
C: Prolonged exposure
O:
PICO 1.21
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: kidNET
C: Waitlist/ treatment as usual
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: kidNET
C: Waitlist/ treatment as usual
O:
PICO 3.21
P: Adults within the first three months post-traumatic event
I: Computerised neurobehavioural training
C: Reading tasks control condition
O:
P: Adults within the first three months post-traumatic event
I: Computerised neurobehavioural training
C: Reading tasks control condition
O:
PICO 1.21
P: Adults with PTSD
I: EMDR
C: Supportive counselling
O:
P: Adults with PTSD
I: EMDR
C: Supportive counselling
O:
PICO 2.21
P: Adults with PTSD
I: Ganaxolone
C: Placebo
O:
P: Adults with PTSD
I: Ganaxolone
C: Placebo
O:
PICO 3.21
P: Adults with PTSD
I: Transcendental meditation
C: Psychoeducation
O:
P: Adults with PTSD
I: Transcendental meditation
C: Psychoeducation
O:
PICO 1.22
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: kidNET
C: Non-directive counselling
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: kidNET
C: Non-directive counselling
O:
PICO 3.22
P: Adults within the first three months post-traumatic event
I: Nurse-led psychological intervention
C: TAU
O:
P: Adults within the first three months post-traumatic event
I: Nurse-led psychological intervention
C: TAU
O:
PICO 1.22
P: Adults with PTSD
I: EMDR
C: Emotional freedom techniques (EFT)
O:
P: Adults with PTSD
I: EMDR
C: Emotional freedom techniques (EFT)
O:
PICO 2.22
P: Adults with PTSD
I: Ketamine
C: Placebo
O:
P: Adults with PTSD
I: Ketamine
C: Placebo
O:
PICO 1.23
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Parent-child relationship enhancement (play therapy)
C: Case management plus individual treatment for parent
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Parent-child relationship enhancement (play therapy)
C: Case management plus individual treatment for parent
O:
PICO 1.23
P: Adults with PTSD
I: EMDR
C: Relaxation training
O:
P: Adults with PTSD
I: EMDR
C: Relaxation training
O:
PICO 2.23
P: Adults with PTSD
I: Neurokinin-1 antagonist
C: Placebo
O:
P: Adults with PTSD
I: Neurokinin-1 antagonist
C: Placebo
O:
PICO 1.24
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Parent-child relationship enhancement (play therapy)
C: Trauma-focused CBT for caregiver and child
O:
P: Children and adolescents with clinically relevant post-traumatic stress symptoms
I: Parent-child relationship enhancement (play therapy)
C: Trauma-focused CBT for caregiver and child
O:
PICO 1.24
P: Adults with PTSD
I: EMDR
C: REM desensitisation
O:
P: Adults with PTSD
I: EMDR
C: REM desensitisation
O:
PICO 1.25
P: Adults with PTSD
I: Non-trauma-focused CBT
C: Waitlist
O:
P: Adults with PTSD
I: Non-trauma-focused CBT
C: Waitlist
O:
PICO 1.26
P: Adults with PTSD
I: Non-trauma-focused CBT
C: Present centred therapy (PCT)
O:
P: Adults with PTSD
I: Non-trauma-focused CBT
C: Present centred therapy (PCT)
O:
PICO 1.27
P: Adults with PTSD
I: Stress inoculation training (SIT)
C: Supportive counselling
O:
P: Adults with PTSD
I: Stress inoculation training (SIT)
C: Supportive counselling
O:
PICO 1.28
P: Adults with PTSD
I: Supportive counselling
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Supportive counselling
C: Waitlist/ treatment as usual
O:
PICO 1.29
P: Adults with PTSD
I: Supportive counselling
C: Psychoeducation
O:
P: Adults with PTSD
I: Supportive counselling
C: Psychoeducation
O:
PICO 1.30
P: Adults with PTSD
I: Present centred therapy
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Present centred therapy
C: Waitlist/ treatment as usual
O:
PICO 1.31
P: Adults with PTSD
I: Psychodynamic therapy
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Psychodynamic therapy
C: Waitlist/ treatment as usual
O:
PICO 1.32
P: Adults with PTSD
I: Written exposure therapy
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Written exposure therapy
C: Waitlist/ treatment as usual
O:
PICO 1.33
P: Adults with PTSD
I: Written exposure therapy
C: Trauma-focused CBT
O:
P: Adults with PTSD
I: Written exposure therapy
C: Trauma-focused CBT
O:
PICO 1.34
P: Adults with PTSD
I: Virtual Reality Therapy
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Virtual Reality Therapy
C: Waitlist/ treatment as usual
O:
PICO 1.35
P: Adults with PTSD
I: Virtual reality therapy
C: Control exposure
O:
P: Adults with PTSD
I: Virtual reality therapy
C: Control exposure
O:
PICO 1.36
P: Adults with PTSD
I: Virtual reality therapy
C: Present centred therapy
O:
P: Adults with PTSD
I: Virtual reality therapy
C: Present centred therapy
O:
PICO 1.37
P: Adults with PTSD
I: Observed and experiential integration (OEI)
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Observed and experiential integration (OEI)
C: Waitlist/ treatment as usual
O:
PICO 1.38
P: Adults with PTSD
I: Relaxation training
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Relaxation training
C: Waitlist/ treatment as usual
O:
PICO 1.39
P: Adults with PTSD
I: Group trauma-focused CBT
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Group trauma-focused CBT
C: Waitlist/ treatment as usual
O:
PICO 1.40
P: Adults with PTSD
I: Group trauma-focused CBT
C: Group present centred therapy
O:
P: Adults with PTSD
I: Group trauma-focused CBT
C: Group present centred therapy
O:
PICO 1.41
P: Adults with PTSD
I: Group trauma-focused CBT
C: Individual trauma-focused CBT
O:
P: Adults with PTSD
I: Group trauma-focused CBT
C: Individual trauma-focused CBT
O:
PICO 1.42
P: Adults with PTSD
I: Group and individual CBT with a trauma focus
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Group and individual CBT with a trauma focus
C: Waitlist/ treatment as usual
O:
PICO 1.43
P: Adults with PTSD
I: Stabilising group treatment
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Stabilising group treatment
C: Waitlist/ treatment as usual
O:
PICO 1.44
P: Adults with PTSD
I: Group interpersonal therapy (IPT)
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Group interpersonal therapy (IPT)
C: Waitlist/ treatment as usual
O:
PICO 1.45
P: Adults with PTSD
I: Couples CBT with a trauma focus
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Couples CBT with a trauma focus
C: Waitlist/ treatment as usual
O:
PICO 1.46
P: Adults with PTSD
I: Guided internet-based trauma focused CBT
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Guided internet-based trauma focused CBT
C: Waitlist/ treatment as usual
O:
PICO 1.47
P: Adults with PTSD
I: Guided internet-based trauma focused CBT
C: Attention control
O:
P: Adults with PTSD
I: Guided internet-based trauma focused CBT
C: Attention control
O:
PICO 1.48
P: Adults with PTSD
I: Guided internet-based trauma-focused CBT
C: Internet-based non-trauma-focused supportive counselling
O:
P: Adults with PTSD
I: Guided internet-based trauma-focused CBT
C: Internet-based non-trauma-focused supportive counselling
O:
PICO 1.49
P: Adults with PTSD
I: Guided internet-based trauma-focused CBT
C: Internet-based psychoeducation
O:
P: Adults with PTSD
I: Guided internet-based trauma-focused CBT
C: Internet-based psychoeducation
O:
PICO 1.50
P: Adults with PTSD
I: Trauma-focused CBT
C: Dialogical exposure therapy (DET)
O:
P: Adults with PTSD
I: Trauma-focused CBT
C: Dialogical exposure therapy (DET)
O:
PICO 1.51
P: Adults with PTSD
I: Interpersonal therapy
C: Relaxation training
O:
P: Adults with PTSD
I: Interpersonal therapy
C: Relaxation training
O:
PICO 1.52
P: Adults with PTSD
I: Metacognitive Therapy
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Metacognitive Therapy
C: Waitlist/ treatment as usual
O:
PICO 1.53
P: Adults with PTSD
I: Stress Inoculation Therapy
C: Waitlist/ treatment as usual
O:
P: Adults with PTSD
I: Stress Inoculation Therapy
C: Waitlist/ treatment as usual
O:
PICO 1.54
P: Adults with PTSD
I: Group trauma-focused CBT
C: Applied muscle relaxation
O:
P: Adults with PTSD
I: Group trauma-focused CBT
C: Applied muscle relaxation
O:
PICO 1.55
P: Adults with PTSD
I: Trauma-focused CBT
C: Supportive counselling
O:
P: Adults with PTSD
I: Trauma-focused CBT
C: Supportive counselling
O:
PICO 1.56
P: Adults with PTSD
I: Trauma-focused CBT
C: Relaxation training
O:
P: Adults with PTSD
I: Trauma-focused CBT
C: Relaxation training
O:
