European Stroke Organisation (ESO) guidelines for the management of spontaneous intracerebral hemorrhage

Published by ESO on Oct 25, 2021

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Abstract

Language

en

PICOS

PICO 1.1

Population
For adults with ICH
Intervention
management on an acute strokeunit
Comparator
care on a general ward
Outcomes

PICO 2.1

Population
For adults with acute ICH
Intervention
altering blood pressure to a particular target or with a specific agent
Comparator
an alternative target or agent
Outcomes

PICO 3.1

Population
For adults with acute ICH not associated with antithrombotic drug use
Intervention
hemostatic drugs
Comparator
standard care
Outcomes

PICO 4.1

Population
For adults with acute ICH associated with antiplatelet drug use
Intervention
hemostatic drugs
Comparator
standard care
Outcomes

PICO 5.1

Population
For adults with ICH associated with anticoagulant drug use
Intervention
hemostatic drugs
Comparator
standard care
Outcomes

PICO 6.1

Population
For adults with supratentorial ICH
Intervention
surgical hematoma evacuation
Comparator
conservative management
Outcomes

PICO 7.1

Population
For adults with supratentorial ICH
Intervention
drainage of cerebrospinal fluid (CSF) by using an external ventricular drain (EVD)
Comparator
no EVD
Outcomes

PICO 8.1

Population
For adults with supratentorial ICH
Intervention
EVD with intraventricular thrombolysis
Comparator
EVD with placebo
Outcomes

PICO 9.1

Population
For adults with infratentorial ICH
Intervention
surgical hematoma evacuation
Comparator
conservative management
Outcomes

PICO 10.1

Population
For adults with ICH
Intervention
intracranial pressure (ICP) monitoring
Comparator
no ICP monitoring
Outcomes

PICO 11.1

Population
For adults with ICH
Intervention
nonsurgical interventions to lower ICP
Comparator
standard care or other treatments
Outcomes

PICO 12.1

Population
For adults with ICH
Intervention
prevention and early treatment of fever
Comparator
conventional fever management
Outcomes

PICO 13.1

Population
For adults with ICH
Intervention
physical or pharmacological interventions to prevent deep vein thrombosis/pulmonary embolism (DVT/PE)
Comparator
standard care
Outcomes

PICO 14.1

Population
For adults with ICH
Intervention
prophylactic antiepileptic drugs (AEDs)
Comparator
no AEDs
Outcomes

PICO 15.1

Population
For patients with ICH suffering from an early seizure
Intervention
long-term AEDs
Comparator
no AEDs
Outcomes

PICO 16.1

Population
For adults with ICH
Intervention
corticosteroids
Comparator
standard care
Outcomes

PICO 17.1

Population
For adults with ICH
Intervention
the use of do-not-attemptresuscitation (DNAR) or withdrawal-of-care (WOC) orders
Comparator
no use of DNAR or WOC orders
Outcomes

PICO 18.1

Population
For adults who had suffered an ICH
Intervention
subsequent blood pressure-lowering therapy
Comparator
standard care
Outcomes

PICO 19.1

Population
For adults with ICH who had been on antithrombotic drugs for thrombotic disease before their ICH
Intervention
continuation of antithrombotic drugs
Comparator
discontinuation of antithrombotic drugs
Outcomes