European Stroke Organisation (ESO) guideline for the diagnosis and treatment of cerebral venous thrombosis – Endorsed by the European Academy of Neurology

Published by ESO on Oct 20, 2021

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Abstract

Language

en

PICOS

PICO 1.1

Population
In patients suspected of CVT
Intervention
MRV
Comparator
digital subtraction angiography
Outcomes

PICO 1.1

Population
In pregnant and puerperal women with CVT
Intervention
the use of anticoagulant therapy
Comparator
Outcomes

PICO 1.1

Population
In patients with CVT
Intervention
a policy of screening for thrombophilia
Comparator
prevents recurrent venous thrombosis
Outcomes

PICO 1.1

Population
In patients with acute cerebral venous thrombosis
Intervention
anticoagulation
Comparator
no anticoagulation
Outcomes

PICO 1.1

Population
In patients with acute or recent CVT
Intervention
AEDs
Comparator
no antiepileptic treatment
Outcomes

PICO 1.1

Population
For patients with acute CVT and symptoms or signs of increased intracranial pressure
Intervention
therapeutic lumbar puncture (LP)
Comparator
standard treatment
Outcomes

PICO 1.2

Population
In patients with acute or recent CVT
Intervention
AEDs
Comparator
no antiepileptic treatment
Outcomes

PICO 1.2

Population
For patients with previous CVT and symptoms or signs of increased intracranial pressure
Intervention
therapeutic LP
Comparator
Outcomes

PICO 2.1

Population
In patient with suspected CVT
Intervention
CT venography
Comparator
digital subtraction angiography
Outcomes

PICO 2.1

Population
In women with prior CVT
Intervention
use of combined oral hormonal contraception
Comparator
Outcomes

PICO 2.1

Population
For patients with acute CVT and symptoms or signs of increased intracranial pressure
Intervention
treatment with carbonic anhydrase inhibitors
Comparator
standard treatment
Outcomes

PICO 2.1

Population
In patients with acute cerebral venous thrombosis
Intervention
LMWH
Comparator
UFH
Outcomes

PICO 2.1

Population
In patients with CVT
Intervention
screening for an occult malignancy
Comparator
Outcomes

PICO 2.2

Population
For patients with previous CVT and symptoms or signs of increased intracranial pressure
Intervention
treatment with carbonic anhydrase inhibitors
Comparator
Outcomes

PICO 3.1

Population
in patients with acute cerebral venous thrombosis
Intervention
thrombolysis
Comparator
anticoagulation
Outcomes

PICO 3.1

Population
For patients with acute CVT and symptoms or signs of increased intracranial pressure
Intervention
does treatment with steroids
Comparator
standard treatment
Outcomes

PICO 3.1

Population
In patients suspected of CVT
Intervention
CT venography
Comparator
MRI and MRV
Outcomes

PICO 3.1

Population
In females with previous history of CVT
Intervention
policy of not contraindicating future pregnancies associated with recurrence of CVT or other VTEs
Comparator
Outcomes

PICO 3.2

Population
For patients with acute CVT and associated inflammatory diseases
Intervention
treatment with steroids
Comparator
standard treatment
Outcomes

PICO 4.1

Population
For patients with CVT
Intervention
treatment with long-term anticoagulation (≥6 months)
Comparator
with treatment with short-term anticoagulation (<6 months)
Outcomes

PICO 4.1

Population
For patients with acute or recent CVT and parenchymal lesion(s) with impending herniation
Intervention
shunting (without other surgical treatment)
Comparator
standard treatment
Outcomes

PICO 4.1

Population
In patients suspected of acute cerebral venous thrombosis
Intervention
D-dimer
Comparator
before neuroimaging
Outcomes

PICO 4.2

Population
For patients with previous CVT
Intervention
treatment with long-term anticoagulation
Comparator
treatment with short-term anticoagulation
Outcomes

PICO 4.2

Population
For patients with acute or recent CVT and hydrocephalus
Intervention
shunting (without other surgical treatment)
Comparator
standard treatment
Outcomes

PICO 5.1

Population
In patients with cerebral venous thrombosis
Intervention
treatment with new oral anticoagulants (NOACs)
Comparator
conventional anticoagulation (heparin and vitamin K antagonists)
Outcomes

PICO 5.1

Population
For patients with acute CVT and parenchymal lesion(s) with impending herniation
Intervention
decompressive surgery (hemicraniectomy or haematoma evacuation)
Comparator
conservative treatment
Outcomes