Management of Neonatal Hypoglycemia

Published by National Neonatology Forum of India on Feb 19, 2024







©National Neonatology Forum of India 2023


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Suggested citation: Management of Neonatal Hypoglycemia. 25 November 2023. New Delhi: National Neonatology Forum of India; 2023 (NNF/2023/CPG/ 2023.5.0). License: CC BY-NC-SA 4.0 


Disclaimers: Due care has been taken to verify the accuracy of all the information in these Clinical Practice Guidelines. However, the contributors, editors, or National Neonatology Forum are not responsible for errors or omissions or any consequences from the application of information provided in this book and give no guarantee concerning the completeness or accuracy of the contents. Application of the information in a situation different from that described in guidelines remains the professional responsibility of the concerned physicians. The guidelines do not endorse any particular brand of equipment or drug. The contributors, editors, and NNF have no affiliation with any of the companies.


The contributors and editors have made great efforts to ensure that all information is according to currently accepted recommendations. However, given the rapidity with which such information changes, the reader is urged to check the latest updates. Updates as and when they occur, shall be posted on the website of NNF and published in the issues of the official journal of NNF, the Journal of Neonatology.




















National Neonatology Forum of India

About us: National Neonatology Forum (NNF), established in 1980, is the professional association of neonatologists of India. It currently has more than 9000 members ( NNF has been instrumental in bringing up neonatology and neonatal care services in India to the forefront. It is actively involved in advocacy, policy-making, capacity-building, and improving quality of care. One of its important mandates is to draw out evidence-based recommendations for neonatal care at different levels. The members of NNF have developed expertise and experience in using GRADE methodology and have released several clinical practice guidelines over the years which are available online ( as well as in Google and Apple Playstores (NNF CPG) as app. 



Office-bearers 2022:

President: Dr. Siddharth Ramji
President-Elect: Dr. Praveen Kumar
Secretary: Dr. Dinesh Tomar
Past President: Dr. Ranjan Kumar Pejaver
Vice President: Dr. Vikram Dutta
Treasurer: Dr. Surender Bisht
Jt. Secretary: Dr. Dinesh Chirla


Office-bearers 2023:

President: Dr. Praveen Kumar
President-Elect: Dr. Sushma Nangia
Secretary: Dr. Surender Bisht
Past President: Dr. Siddharth Ramji
Vice President: Dr. Alok Bhandari
Treasurer: Dr. Amit Upadhyay
Jt. Secretary: Dr. Srinivas Murki
Immediate Past Secretary General: Dr. Dinesh Tomar




PICO 5.1

Neonates (any gestational age) with symptomatic hypoglycemia
Initial management with mini-bolus followed by continuous infusion
Continuous dextrose infusion alone

PICO 6.1

Neonates at risk for hypoglycemia
Lower threshold group (Plasma glucose < 36 mg/dL)
Higher threshold group (Plasma glucose < 47 mg/dL)

PICO 8.1

Oral dextrose gel to prevent hypoglycaemia in at-risk neonates
Dextrose gel

PICO 9.1

Oral dextrose gel for the treatment of hypoglycaemia in newborn infants
Dextrose gel