WHO guideline on the prevention and management of wasting and nutritional oedema (acute malnutrition) in infants and children under 5 years

Published by World Health Organization on Mar 6, 2024

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Abstract

Language

en-gb

PICOS

PICO 3.1

Population
infants and children with severe wasting and/or nutritional oedema
Intervention
standard WHO low-osmolarity ORS
Comparator
ReSoMal
Outcomes

PICO 3.1

Population
infants <6 months with severe wasting and/or nutritional oedema
Intervention
diluted F-100
Comparator
infant formula
Outcomes

PICO 3.1

Population
infants and children with wasting or nutritional oedema
Intervention
psychosocial stimulation
Comparator
routine care
Outcomes

PICO 3.2

Population
infants <6 months with severe wasting and/or nutritional oedema
Intervention
F-100
Comparator
infant formula
Outcomes

PICO 3.2

Population
infants and children with severe wasting or nutritional oedema
Intervention
unconditional cash transfers
Comparator
routine care
Outcomes

PICO 3.3

Population
infants <6 months with severe wasting and/or nutritional oedema
Intervention
F-100
Comparator
diluted F-100
Outcomes

PICO 3.3

Population
infants and children with severe wasting and/or nutritional oedema
Intervention
daily oral co-trimoxazole prophylaxis
Comparator
placebo
Outcomes

PICO 4.1

Population
infants and children with severe wasting and/or nutritional oedema who are not tolerating F-75 or F-100
Intervention
hydrolyzed formulas
Comparator
standard therapeutic feeds including F-75 and F-100
Outcomes

PICO 4.1

Population
infants and children at risk of wasting and nutritional oedema
Intervention
MQ-LNS and LQ-LNS
Comparator
control
Outcomes

PICO 4.2

Population
infants and children at risk of wasting and nutritional oedema
Intervention
SQ-LNS
Comparator
control
Outcomes

PICO 4.3

Population
infants and children at risk of wasting and nutritional oedema
Intervention
blanket approach
Comparator
targeted approach
Outcomes

PICO 4.4

Population
infants and children at risk of wasting and nutritional oedema
Intervention
MNPs
Comparator
control
Outcomes

PICO 5.1

Population
infants and children >6 months with severe wasting or nutritional oedema
Intervention
reduced quantity of ready-to-use therapeutic food (RUTF)
Comparator
current ready-to-use therapeutic food (RUTF) quantity
Outcomes

PICO 6.1

Population
infants and children >6 months with moderate wasting
Intervention
specially formulated foods
Comparator
counselling alone
Outcomes

PICO 6.2

Population
infants and children >6 months with moderate wasting
Intervention
locally produced fortified blended foods (FBFs)
Comparator
lipid-based nutrient supplements (LNS)
Outcomes

PICO 6.3

Population
infants and children >6 months with moderate wasting
Intervention
Corn Soy Blend (CSB)
Comparator
lipid-based nutrient supplements (LNS)
Outcomes

PICO 6.4

Population
infants and children >6 months with moderate wasting
Intervention
improved fortified blended foods (FBFs)
Comparator
lipid-based nutrient supplements (LNS)
Outcomes

PICO 6.5

Population
infants and children >6 months with moderate wasting
Intervention
improved fortified blended foods (FBFs)
Comparator
locally produced fortified blended foods (FBFs)
Outcomes

PICO 6.6

Population
infants and children >6 months with moderate wasting
Intervention
ready-to-use therapeutic foods (RUTF)
Comparator
ready-to-use supplementary foods (RUSF)
Outcomes

PICO 7.1

Population
infants and children with wasting and nutritional oedema
Intervention
identification and management of wasting and nutritional oedema by community health workers
Comparator
identification and management of wasting and nutritional oedema by health professionals
Outcomes